Precise media separation in liquid chromatography
Choosing the right valve is crucial when it comes to liquid chromatography. Discover why our Type 2036 Robolux valves are the right choice.
Your advantages with our multi-way diaphragm valve Type 2036 Robolux
- Increased production efficiency through accelerated processes thanks to minimum dead space
- Maximum removal of the chromatography product thanks to safe distribution and removal of the product
- Significant minimisation of downtime due to easy and quick replacement of the diaphragm
- Process reliability: costly mixing of media is avoided
Downstream processing in biochemical manufacturing
In the chemical or bioprocess engineering industry, products must be separated from a complex media mixture and freed from impurities. This is an important step in the entire chain of downstream processing to guarantee a product with the required purity.
Collaboration to the benefit of our customers: Partnering with the team at YMC Process Technologies to create solutions to pharmaceutical manufacturing challenges and meet FDA challenges in record time. The combined expertise of Burkert and YMC allowed for rapid acceleration of continuous bioprocess flow in chromatography applications. See more in this brief video.
The stationary and mobile phase of liquid chromatography
The precise and safe purification of substances using chromatography is an essential step in the manufacture of fine chemicals. For this purpose, a bio-physical principle is applied which takes advantage of the various flow properties and flow velocities of the components. The individual components are separated between a stationary phase (the tubular column in a column) and a mobile phase, which flows through the stationary packing (in this case a liquid).
Operation principle of chromatography
To purify (downstream processing) a liquid from various components, it is fed into a chromatography process. Due to the various velocities at which all liquids are pumped through the plant, the individual components can be separated as a result of the different flow properties and varying interactions between the stationary and the mobile phase of the substances.
Why is chromatography so important?
It can be used to separate complex media mixtures with great precision. Even very complicated molecules such as proteins can, e.g., be gently separated from each other using chromatography. Under no circumstances should contamination or mixing of media occur. Choice of the right valve is a decisive factor here, as it controls and distributes the media into and out of the chromatography column – precisely and efficiently.
Designed for the control of ultra-pure, sterile and aseptic media, the Robolux Multiway Diaphragm Valve Type 2036 offers the ideal solution for chromatography processes.
Robolux multiway diaphragm valve, pneumatically operated
- Extremely compact and space-saving design
- Reduced installation costs
- Reduced number of valves and welds
Your benefits in detail
Diaphragm valves with minimized dead space - save time and money
The smaller the dead space in the valve, the lower the probability of media mixing and the faster the actual process. Compared to conventional solutions, Robolux allows you to save 68 ml of liquid per distributor in each process thanks to an extremely reduced dead space. Discover in our chromatography flyer how you can reduce your operating costs.
Compact design – improved plant efficiency with the same footprint
Due to the compact design of the Robolux, you need less space in the plant. In the event of maintenance or troubleshooting, employees are able to get to the cause of the problem faster. In addition, plant efficiency can be enhanced without having to increase the production area.
Conventional valve distributor = 57.416 cm³
Conventional valve block solution = 47.430 cm³
Robolux valve = 11.880 cm³
Do you want to minimize downtime and increase plant availability?
Read our flyer to discover how you can save time and money on maintenance and replacement of the diaphragm when using Robolux compared to conventional valve solutions. Download the flyer now and benefit from the advantages.